IMMUNO-model Second Annual Conference
Monday, May 13th, 2024
| 14:00 – 18:30 | Core group meeting: only for core group members (Venue: Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava) |
14th and 15th May, 2024
“IMMUNO-model Second Annual Conference: From Pre-clinical Models to the Search for Biomarkers in Immuno-Oncology”
(Venue: HubHub, Twin City C, Mlynské nivy 7816/14, Bratislava)
Tuesday, May 14th, 2024
| 08:00 – 8:30 | Registration |
| 08:30 – 8:45 | Welcome Silvia Pastoreková, General Director of the Biomedical Research Center of the Slovak Academy of Sciences Eva Martínez Balibrea, IMMUNO-model COST Action Chair |
| 08:45 – 9:30 | Opening Keynote Lecture Leticia Oliveira-Ferrer: IO-Resp: A collaborative project for prediction of treatment response to immuno-oncological agents in ovarian cancer |
Scientific session WG1 Chairs: Hanne Haslene-Hox, Lucia Kučerová | |
| 09:30 – 10:45 | Bruno Sarmento: Multicellular 3D immunospheroid models for preclinical development of nanomedicines Marcin Krzykawski: Novel 3D Cell Culture Models for Immuno-Oncology studies Uzma Hasan: Functional and spatial analyses of patient-derived tumor fragments to dissect response and resistance mechanisms ex vivo to immune checkpoint inhibitors in cancers |
| 10:45 – 11:15 | Coffee break with Poster session WG1 + WG2 |
Selected abstracts | |
| 11:15 – 12:00 | Ana Mitrovic: Inhibition of cathepsins B and X as an approach to impair cancer stem cells Marta Maleszewska: Epigenetic inhibitors as potential agents modulating immune response in glioma Metka Novak: Glioblastoma organoid model as a personalized tool for standard and immuno-therapy research |
| 12:00 – 12:05 | Emanuela Senjor: Introducing the IMMUNO-model Protocol Database Task Force |
| 12:05 – 13:00 | Discussion about the WG1 activities led by Devrim Pesen Okvur & Cristiana Tanase |
| 13:00 – 14:00 | Lunch break |
Scientific session WG2 Chairs: Emmet McCormack, Lukasz Skalniak | |
| 14:00 – 15:15 | Mangala Srinivas: In vivo imaging for quantitative tracking of immune cells Calum Leitch: Utilising preclinical animal models and single-cell analysis for cancer immunotherapy studies Juan Carlos Rodriquez-Manzaneque:Unveiling new extracellular matrix immunomodulatory actions within the tumor microenvironment: the axis ADAMTS1/NIDOGEN1 |
Selected abstracts | |
| 15:15 – 16:00 | Serkan Sen: Do Statins Influence Prognosis in Patients With Advanced Non-Small Cell Lung Cancer Treated With Nivolumab? Chiara Calarusso: Identification of mechanism/s of resistance to immunotherapy using a mouse model of low tumor mutational burden Eleni Douni: Modeling breast cancer and bone metastasis in TgRANKL mice |
| 16:00 – 16:30 | Coffee break with Poster session WG1 + WG2 |
| 16:30 – 17:30 | Discussion about the WG2 activities led by Johannes Haybaeck & Emmet McCormack |
| 18:30 | Dinner (WERK restaurant) |
Wednesday, May 15th, 2024
| 08:30 – 9:15 | Keynote lecture Emmanuel Donnadieu: Predicting safety and efficacy of engineered T cells using an ex vivo human model |
Scientific session WG3 Chairs: Marleen Ansems, Denis Collins | |
| 09:15 – 10:30 | Anguraj Sadanandam: Stratification of a Panel of Mouse Models of Pancreatic Cancer using Immune Landscape and Extra-cellular Matrix to Predict Response to Synthetic IL-12 Therapy Denis Collins: Investigating the immune profile of early stage HER2+ breast cancer patients receiving chemotherapy and HER2-targeted therapies Osman Ugur Sezerman:Multiomics AI models to predict immunotherapy response and biomarkers |
| 10:30 – 11:00 | Coffee break with Poster session WG3 + WG4 |
Selected abstracts | |
| 11:00 – 11:45 | Lucia Kučerová: DNase treatment affects tumor angiogenesis and augments cytotoxic effect of cisplatin in chemoresistant germ cell tumors Ana Maria Enciu:Various patient-derived Glioblastoma 3D tumor models and their downstream application opportunities Talip Zengin: In-Silico Cancer Immunology Cohort Discovery Using TCGAnalyzeR |
| 11:45 – 12:45 | Discussion about the WG3 activities led by Marleen Ansems & Maurizio Callari |
| 12:45 – 13:45 | Lunch break |
Scientific session WG4 Chairs: Laura Belver, René Winkler | |
| 13:45 – 15:00 | Christian P. Pallasch: Therapy Resistance in TP53-deficient B-cell Malignancies – the role of EVs and PD-L1 suppressing Macrophages (online lecture) Magdalena Winiarska: The CAR costimulatory domain influences the process of CAR-CD19 resistance development in lymphoma and B-ALL Víctor M. Díaz Cortés: Pre-clinical validation of humanized CAR-Ts cells in the industry: experiences from the bench to the bedside |
Selected abstracts | |
| 15:00 – 15:45 | Jessica Dal Col: Exploring the role of microRNAs in intercellular communication during Immunogenic Cell Death Anamaria Bancos: Retinoid Differenciating agents induce Maturation of MDS cells in vitro Klaudyna Fidyt: The identification of potential targets for CAR-based therapy using transcriptomic and proteomic approaches |
| 15:45 – 16:15 | Coffee break with Poster session WG3 + WG4 |
| 16:15 – 17:15 | Discussion about the WG4 activities led by Laura Belver & Rui Bergantim |
| 17:15 – 17:30 | Closing remarks Eva Martínez Balibrea |